Equipment
3D X-ray nanomicroscope Zeiss Xradia Versa 620
Zeiss, Germany
Description and specifications
X-ray tomography (micro/nano CT) for non-destructive analysis of the internal structure of samples.
Specifications: 30-160 kV, 1- 25 W. Magnification: zoom and optical lenses (0.4x, 4x, 20x, 40x).
Maximum sample size 10x10x10 cm3, for higher resolutions a smaller sample size is required. Maximum resolution 500 nm, voxel size 40 nm. Realistic resolution for samples larger than 3x3x3 mm3 is approx. 3 µm.
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Epifluorescent microscope Leica DMI 6000B with incubation chamber Okolab for live cell imaging and tracking.
Leica Microsystems, Nemčija
Okolab, Italija
The purchase was cofinanced by the Ministry of education, Science and Sport (Republic of Slovenia) and the European fund for regional development.
Description and specifications
Leica DMI 6000B epifluorescence microscope, with automated moving stage and cell culture incubation chamber (Okolab).
Imaging
Magnification: 10x, 1.5x
Resolution: 2.3 MP (1920 x 1200 pixels)
Working range (Z): 8801 µm
Spectra for excitation and emission in fluorescence:
GFP – Excitation: ~470 nm, Emission: ~520 nm.
TX2 (Texas Red) – Excitation: ~560 nm, Emission: ~620 nm.
A4 (DAPI) – Excitation: ~360 nm, Emission: ~460 nm.
RHO (Rhodamine) – Excitation: ~540 nm, Emission: ~570 nm.
Table
Compatible containers:
Standard microtiter plates,
4x petri dishes, 35mm diameter,
2x objective glass
Working surface 130x50mm
Incubation
0-20% CO2
0-50°C
Passive humidification
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Atomic force microscopy
Logan Sytem 912-6,
Logan Instruments Corp., USA
Description and specifications
Mikroskopija na atomsko silo (AFM) je napredna slikovna tehnika, ki se uporablja za vizualizacijo in manipulacijo površin na nano ravni z visoko natančnostjo. Za razliko od običajne svetlobne mikroskopije deluje AFM s skeniranjem ostre konice sonde po površini vzorca, pri čemer zaznava majhne sile med konico in atomi ali molekulami na površini. Ta metoda omogoča opazovanje topografije, morfologije in mehanskih lastnosti površin v nanometrskem merilu.
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Vitaprint 3D bioprinter
IRNAS d.o.o., Slovenia
Description and specifications
Pneumatically powered 3D extrusion bioprinter.
3 modular extrusion heads, compatible with 5cc cartridges, heating to 80°C.
Working pressure range: 1-9bar
Working area: 130 x 200mm
Minimum step size: 20 µm (XYZ)
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Automatic Franz Diffusion Cell System
Logan Instruments Corp., USA
Description and specifications
Standard system for simulating the release of chemical substances and active pharmaceutical ingredients from transdermal and topical delivery systems and open wound applications. It allows release studies in 6 diffusion cells of 5 and 15 ml volume, with temperature control and automatic sampling.
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ACQUITY Arc HPLC system
Waters 1525,
Waters Corp., USA
The purchase of the equipment was co-financed by the Public Agency for Scientific Research and Innovation of the Republic of Slovenia and the Faculty of Medicine, University of Maribor.
Decsription and specifications
The HPLC system allows the separation, identification and quantification of components in a mixture based on interactions between the mobile and stationary phases. The high resolution and sensitivity provide accurate and reproducible results, while the improved detection efficiency allows reliable analysis even at very low concentrations of analytes. The system is equipped with robust software that allows intuitive operation and efficient data analysis. The HPLC is coupled to a PDA detector that allows monitoring of analytes in the spectral range 200-800 nm. For molecules that do not absorb light in the UV-VIS range (e.g. monosaccharides), alternative detection methods such as a refractive index detector (RI detector) are used.
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Cryostat
Cryostar NX50,
Thermo Scientific, USA
Description and specifications
Cryostar NX50 is a cryostat suitable for rapid and well-controlled preparation of micron-scale histological sections (0.5-100µm). The adjsutable, clean design and interface provide a user-friendly experience and rapid adoption of the instrument.
Contact person
Tomaž Martini
xMAP Multiplex Immunoassay System
MAGPIX,
Luminex, USA
The purchase of the equipment was co-financed by the Public Agency for Scientific Research and Innovation of the Republic of Slovenia and the Faculty of Medicine, University of Maribor.
Description and specifications
Luminex MAGPIX is a compact, high-performance multiplex analytical platform designed for fast and efficient quantitative analysis of multiple biological analytes simultaneously. The device uses advanced xMAP technology, which enables the simultaneous detection of up to 50 different analytes in a single sample, ideal for research, clinical diagnostics and biomarker testing.
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Biopixlar microfluid printer
Fluicell, Sweden
Description and specifications
Microfluidic bioprinter for the application of cell suspension liquids.
Theoretical spatial resolution: 2 µm (XY)
Working area: 30x30mm
Working pressure range
Continuous monitoring with inverted microscope:
Bright field
Fluorescence (LED in spectra for blue (ex: 370-410 nm; em: 429-462 nm), green (ex: 473-491 nm; em: 502-561 nm) and red (ex: 580-598 nm; em: 612-680 nm)
Contact person
Ajda Godec
ICP-OES
Agilent 5110 VDV, USA
Description and specifications
Analysis of trace elements in various liquid samples.
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PalmSens4
PalmSens, Netherlands
Description and specifications
The PalmSens4 is a compact and versatile potentiostat, galvanostat and impedance analyser designed for both laboratory and field applications. It offers a wide potential range of ±5 V or ±10 V and supports current measurements from 100 pA up to 10 mA, ensuring high resolution and low noise. The device is powered via USB or an internal LiPo battery and offers connectivity via USB or Bluetooth, which facilitates floating measurements.
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Cary 630 FTIR,
Agilent Technologies, USA
Description and specifications
A system for evaluating the spectroscopic properties of matter, visible in the IR field (identification of the substance and real-time follow-up of structural changes)
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1. Cary 60 UV/VIS, Agilent Technologies, USA
2. NanoDrop™ 2000, Thermo Fisher Scientific
Description and specifications
1. A system for determination of the concentration of substances in solution, as well as the kinetics of processes taking place in the liquid state.
2. Microvolume spectrophotometer used to quantify and assess purity of DNA, RNA, protein and more.
Digital hydraulic press
CrushIR,
PIKE Technologies, UK
Description and specifications
Spin-coating system
SPIN-150i-NPP,
S.P.S. Vertriebs GmbH, Germany
Description and specifications
Inverted optical microscope
Axiovert 40,
Zeiss, Germany
Description and specifications
Varioskan,
Thermo Fisher Scientific
Description and specifications
MUSE,
EMD Millipore, USA
Description and specifications
BenchPro™ 4100 Card Processing Station,
Thermo Fisher Scientific
Description and specifications
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