Equipment

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3D bioprinting

Vitaprint,
 IRNAS Ltd, Slovenia

A customizable 3D bioprinting system with 3 individual extrusion heads (pneumatic, heated) and two 3-channel microfluidic printheads (pneumatic). Used routinely for scaffold fabrication using hydrogels, polymer solutions or thermoplastic polymers.
Imaging flow cytometry
Amnis Imagestream X mkII, EMD Millipore, USA
Imaging flow cytometry, which combines regular flow cytometry with multi-channel cell visualization.

Automatic Franz Diffusion Cell System 

Logan Sytem 912-6,
Logan Instruments Corp., USA
A standard system designed to simulate transdermal and topical administration routes, as well application on open wounds. It enables use in applications, where it is necessary to test in smaller volumes (5 to 15 mL)

Fluorescence microscopy

(1) EVOS FL Cell Imaging System,
Thermo Fisher Scientific

(2) Leica DMI6000 B coupled with DMC6200 camera,
Leica Microsystems, Germany

(1) Fully integrated, digital, inverted imaging system for four-color fluorescence and transmitted-light applications.

(2) Inverted microscope for biomedical research offers Differential Interference Contrast for relief imaging of specimens with varying indices of refraction. It is ideal for fluorescence, live cell, time-lapse imaging, high-speed multi-fluorescence optical sectioning, and micromanipulation. DMC6200 camera with pixel shit technology incorporates a state-of-the-art CMOS sensor which has a 5.86 µm pixel size, 2.3 megapixels sensor resolution and an dynamic range of 73 dB (4000:1).

New Generation Sequencer

MiSeq™ System,

Illumina, USA

The MiSeq System is an integrated instrument that performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting in a single run.

xMAP Multiplex Immunoassay System

MAGPIX,
 Luminex, USA

The MAGPIX System allows for multiplexing up to 50 different tests in a single reaction volume and reads a 96-well plate in just 60 minutes.

HPLC system

Waters 1525,
 Waters Corp., USA

Separation, identification and quantification of components in solution.

Atomic force microscopy

Logan Sytem 912-6,
 Logan Instruments Corp., USA

A standard system designed to simulate transdermal and topical administration routes, as well application on open wounds. It enables use in applications, where it is necessary to test in smaller volumes (5 to 15 mL) 

ICP-OES

Agilent 5110 VDV,
 USA

Trace element analysis in various liquid samples. 

Quantitative real-time PCR

QuantStudio 12K Flex,
 Applied Biosystems, USA

High-throughput PCR platform that provides various methods for gene detection, gene expression analysis, genetic variation analysis and array data validation.

Biochemical analysis

Cobas c 111,
 Roche, Switzerland

Compact solution for clinical chemistry testing in laboratories running up to 50 samples per day or a throughput up to 25,000 tests per year. 

Cryostat 

Cryostar NX50,
 Thermo Scientific, USA

Cryostar NX50 is a cryostat suitable for rapid and well-controlled preparation of micron-scale histological sections. The adjsutable, clean design and interface provide a user-friendly experience and rapid adoption of the instrument.
Infrared spectroscopy

Cary 630 FTIR,
 Agilent Technologies, USA

A system for evaluating the spectroscopic properties of matter, visible in the IR field (identification of the substance and real-time follow-up of structural changes)
UV/VIS spectrophotometry

1. Cary 60 UV/VIS, Agilent Technologies, USA
 2. NanoDrop™ 2000, Thermo Fisher Scientific

1. A system for determination of the concentration of substances in solution, as well as the kinetics of processes taking place in the liquid state.

 2. Microvolume spectrophotometer used to quantify and assess purity of DNA, RNA, protein and more.

Digital hydraulic press

CrushIR,
PIKE Technologies, UK

Laboratory press for production of low batches of tablets

Spin-coating system

SPIN-150i-NPP,
 S.P.S. Vertriebs GmbH, Germany

Modern spin coater for precise thin film preparation, useful especially for preparation of all kinds of coatings (even multi-layer) for various applications, e.g. model wound dressings.

Inverted optical microscope

Axiovert 40,
 Zeiss, Germany

Inverted optical microscope for cell culture applications
Microplate reader

Varioskan,
 Thermo Fisher Scientific

Fast determination of fluorescence, luminescence etc. of a large number of samples.
Cell analyzer

MUSE,
 EMD Millipore, USA

Cell counter and analyser with a versatile applicability options. In can be used to develop own methods or use commercial kits to test for different cell related phenomena (e.g. phagocytosis, apoptosis, …)
Western blot

BenchPro™ 4100 Card Processing Station,
 Thermo Fisher Scientific

For automated processing of routine fluid processing steps for western blot protocols.
pH, 02 meter
pH, 02, temperature microsensor, Unisense Denmark
The pH and 02 electrode with tip size of 10 µm allows for a fast and reliable non-destructive measurement of pH and oxygen at high spatial resolution in a wide range of microenvironments.

Future team member

Student/Researcher
A motivated, proactive, team player interested in biomedical engineering and/or related topics such as materials science, cell and molecular biology, regenerative medicine, etc. Someone who is eager to learn and wants to join an enthusiastic, friendly and interdisciplinary team, either as a Master, PhD or post-doc candidate.

Join us!

Bridging the gap between academia and industry.

Service activities we offer to the industry

Preparation of (bio) polymer coatings

Preparation of 3D printed structures from (bio) polymers

Chemical and structural characterization of (bio) polymer products

Biocompatibility studies

Development of in vitro models of human tissues and diseases

Development of pharmacological delivery systems

Testing of pharmacologically active substances of natural and synthetic origin

Testing the pharmacological and toxic effects of various physical and chemical factors

Biochemical analyzes of biological samples

Development and testing of (bio) sensors

Partners