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3D rentgenski nanomikroskop Zeiss Xradia Versa 620

3D rentgenski nanomikroskop Zeiss Xradia Versa 620, za napredno digitalno vizualizacijo oblike in notranje strukture vzorcev širokega nabora materialov z možnostjo segmentacije različnih faz ter z ločljivostjo na sub-mikronskem nivoju. To omogoča preučevanje tako bioloških vzorcev, polimerov, kovin in drugih materialov ter metamaterialov. Dodatno funkcionalnost sistema omogoča in-situ sistem za kvazistatično mehansko preizkušanje vzorcev s pomočjo kompresijskih in nateznih testov za preučevanje deformacije vzorcev ob mehanskih obrementivah.

Nakup opreme sta sofinancirala Republika Slovenija, Ministrstvo za izobraževanje, znanost in šport in Evropska unija iz Evropskega sklada za regionalni razvoj.

3D bioprinting

Vitaprint,
 IRNAS Ltd, Slovenia

A customizable 3D bioprinting system with 3 individual extrusion heads (pneumatic, heated) and two 3-channel microfluidic printheads (pneumatic). Used routinely for scaffold fabrication using hydrogels, polymer solutions or thermoplastic polymers.
Imaging flow cytometry
Amnis Imagestream X mkII, EMD Millipore, USA
Imaging flow cytometry, which combines regular flow cytometry with multi-channel cell visualization.

Automatic Franz Diffusion Cell System 

Logan Sytem 912-6,
Logan Instruments Corp., USA
A standard system designed to simulate transdermal and topical administration routes, as well application on open wounds. It enables use in applications, where it is necessary to test in smaller volumes (5 to 15 mL)
Invertni mikroskop Leica DMI6000B z avtomatizirano mizico in Okolabovim inkubatorjem za celične culture

Leica Microsystems, Nemčija

Invertni mikroskop Leica DMI6000B z avtomatizirano mizico in Okolabovim inkubatorjem za celične kulture omogoča slikanje ter sledenje živih celic s kombinacijo zajema slik v svetlem polju, faznem kontrastu in epifluorescenco. Omogoča časovno sledenje s prostorskim in časovnim šivanjem pridobljenih slik visoke ločljivosti v X,Y in Z koordinatah z možnostjo 3D rekonstrukcije vzorcev. Integriran Okolabov inkubator zagotavlja nadzorovane pogoje za gojenje celic za dolgoročno ohranjanje bioloških vzorcev v mikroskopu, kar je idealno za poskuse diferenciacije tkiv in druge biomedicinske aplikacije.
New Generation Sequencer

MiSeq™ System,

Illumina, USA

The MiSeq System is an integrated instrument that performs clonal amplification, genomic DNA sequencing, and data analysis with base calling, alignment, variant calling, and reporting in a single run.

xMAP Multiplex Immunoassay System

MAGPIX,
 Luminex, USA

The MAGPIX System allows for multiplexing up to 50 different tests in a single reaction volume and reads a 96-well plate in just 60 minutes.

HPLC system

Waters 1525,
 Waters Corp., USA

Separation, identification and quantification of components in solution.

Atomic force microscopy

Logan Sytem 912-6,
 Logan Instruments Corp., USA

A standard system designed to simulate transdermal and topical administration routes, as well application on open wounds. It enables use in applications, where it is necessary to test in smaller volumes (5 to 15 mL) 

ICP-OES

Agilent 5110 VDV,
 USA

Trace element analysis in various liquid samples. 

Quantitative real-time PCR

QuantStudio 12K Flex,
 Applied Biosystems, USA

High-throughput PCR platform that provides various methods for gene detection, gene expression analysis, genetic variation analysis and array data validation.

Biochemical analysis

Cobas c 111,
 Roche, Switzerland

Compact solution for clinical chemistry testing in laboratories running up to 50 samples per day or a throughput up to 25,000 tests per year. 

Cryostat 

Cryostar NX50,
 Thermo Scientific, USA

Cryostar NX50 is a cryostat suitable for rapid and well-controlled preparation of micron-scale histological sections. The adjsutable, clean design and interface provide a user-friendly experience and rapid adoption of the instrument.
Infrared spectroscopy

Cary 630 FTIR,
 Agilent Technologies, USA

A system for evaluating the spectroscopic properties of matter, visible in the IR field (identification of the substance and real-time follow-up of structural changes)
UV/VIS spectrophotometry

1. Cary 60 UV/VIS, Agilent Technologies, USA
 2. NanoDrop™ 2000, Thermo Fisher Scientific

1. A system for determination of the concentration of substances in solution, as well as the kinetics of processes taking place in the liquid state.

 2. Microvolume spectrophotometer used to quantify and assess purity of DNA, RNA, protein and more.

Digital hydraulic press

CrushIR,
PIKE Technologies, UK

Laboratory press for production of low batches of tablets

Spin-coating system

SPIN-150i-NPP,
 S.P.S. Vertriebs GmbH, Germany

Modern spin coater for precise thin film preparation, useful especially for preparation of all kinds of coatings (even multi-layer) for various applications, e.g. model wound dressings.

Inverted optical microscope

Axiovert 40,
 Zeiss, Germany

Inverted optical microscope for cell culture applications
Microplate reader

Varioskan,
 Thermo Fisher Scientific

Fast determination of fluorescence, luminescence etc. of a large number of samples.
Cell analyzer

MUSE,
 EMD Millipore, USA

Cell counter and analyser with a versatile applicability options. In can be used to develop own methods or use commercial kits to test for different cell related phenomena (e.g. phagocytosis, apoptosis, …)
Western blot

BenchPro™ 4100 Card Processing Station,
 Thermo Fisher Scientific

For automated processing of routine fluid processing steps for western blot protocols.
pH, 02 meter
pH, 02, temperature microsensor, Unisense Denmark
The pH and 02 electrode with tip size of 10 µm allows for a fast and reliable non-destructive measurement of pH and oxygen at high spatial resolution in a wide range of microenvironments.

Bodoči sodelavec/sodelavka

Študent(ka)/raziskovalec(ka)

Motiviran, proaktiven, timski igralec, ki ga zanima biomedicinski inženiring in/ali sorodne teme, kot so znanost o materialih, celična in molekularna biologija, regenerativna medicina itd. Nekdo, ki se želi učiti in se želi pridružiti navdušeni, prijazni in interdisciplinarni ekipi kot magistrski, doktorski ali podoktorski kandidat.

Pridružite se nam!

Povezovanje z industrijo.

Storitvene aktivnosti, ki jih ponujamo industriji

Priprava premazov iz (bio) polimerov

Priprava 3D tiskanih struktur iz (bio) polimerov

Kemijska in strukturna karakterizacija izdelkov iz (bio) polimerov

Študije biokompatibilnosti

Razvoj in vitro modelov humanih tkiv in bolezni

Razvoj farmakoloških dostavnih sistemov

Testiranje farmakoloških učinkovin naravnega in sinteznega izvora

Testiranje farmakoloških in toksičnih učinkov različnih fizikalnih in kemijskih dejavnikov

Biokemijske analize bioloških vzorcev

Razvoj in testiranje (bio)senzorjev

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