The aim of the project is to develop a platform of several different printable bioinks for 3D printing of materials and stem cells simultaneously. We are additionally working on protocols for the analysis of the prepared materials in terms of determining changes in phenotype before and after embedding and during cell growth itself at different time points after 3D printing.

The purpose of the above is twofold, on the one hand to understand how the phenotype of stem cells can be influenced by altering the chemistry, morphology and structure of 3D printed materials, which could lead to a number of new therapeutic options in the field of regenerative medicine, and on the other hand to understand the orchestration of stem cell function through their paracrine and autocrine communication and on a population of cells within a certain environment (e.g. scaffold), based on the optimisation of protocols for monitoring phenotype changes. Such findings will contribute significantly to the development of the field of regenerative medicine and possibly increase the potential of future products for faster implementation in clinical practice.