Doc. Dr. Tomaž Martini

Researcher

Tomaž focuses his research on hepatic physiology, organismal metabolism, computational analysis of large biological datasets and circadian rhythms, with the overarching goal of gaining deeper insights into pressing human diseases, as well as contributing to the development of improved diagnostic tools and novel therapeutic strategies. His work involves the use of advanced mouse models, including tissue- and cell-type-specific genetic manipulations, to unravel complex biological mechanisms and their relevance to health and disease.

After completing his masters in pharmacy at the University of Ljubljana, Slovenia, Tomaž performed his PhD in biochemistry at the University of Fribourg in Switzerland. During his doctoral research under Professor Urs Albrecht, he conducted studies in the fields of neurobiology, metabolism, and circadian rhythms, primarily using genetically modified mouse models.

Following his doctorate, Tomaž performed postdoctoral research at the Swiss Federal Technology Institute of Lausanne (EPFL), where he worked on liver physiology at the single cell level, with specific focus on hepatic very-low-density lipoprotein (VLDL) metabolism.

Tomaž’s specialized technical skill set includes stereotactic brain surgery in mice, complex perfusion techniques, in vivo genetic manipulation, and single-cell sequencing—from experimental execution in animals to downstream computational analysis. These methodologies form the backbone of his research, enabling high-resolution investigation of physiological processes across molecular, cellular, and systemic levels.

Since December 2024, he has been employed at the Institute of Biomedical Sciences, Faculty of Medicine, where he continues to focus on the newly discovered hepatic VLDL cycle.

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